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The Trial

Young people fare disproportionately poorly across the HIV care continuum compared to other age-groups; the prevalence of undiagnosed HIV is higher and coverage of and adherence to antiretroviral therapy is lower, resulting overall in worse HIV outcomes. Young people encounter many barriers to accessing health facilities. In addition, HIV is often not their top priority.



We aim to use an innovative approach to address these barriers:

  • Provision of services in community-based settings and configuration of services to create "youth appeal"

  • Integrated services: Providing HIV testing as well as treatment and adherence support; and integration with other services that youth need and want

Project Aims

The aim of the CHIEDZA Project is to investigate the impact of a community-based package of integrated HIV services and sexual and reproductive health services (SRH), and general health counselling, for youth on HIV and other health outcomes in a high HIV prevalence setting.


Objectives are:

  • To measure the impact of a community-based intervention incorporation delivery of  HIV (including HIV testing, treatment and adherence support) and SRH services and health counselling, for 16-24 year olds, on population-level HIV outcomes​

  • ​To estimate the cost and cost-effectiveness of the intervention

  • To conduct a mixed-methods process evaluation of the intervention to inform scalability and sustainability​

  • To estimate population-level prevalence of key health-related

  • risk factors and behaviours in youth 

Study Design

We are conducting a cluster randomised trial in three provinces of Zimbabwe (Harare, Bulawayo and Mashonaland East). A total of 24 study clusters is randomised, in a 1:1 allocation ratio in each province, to:

1. Control Arm - Existing, routine services OR

2. Intervention Arm - A package of health services for16-24 year olds in community-based settings over two years


Cluster = geographically-defined area which has a community centre (where the services will be delivered) and a primary care clinic.

The outcomes will be determined through an end-line population-based survey of 24,000 youth (1000/cluster).

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CHIEDZA Services 
Project Outcomes

Secondary outcomes (corresponding to UNAIDS 90-90-90 targets)

  • % of youth with HIV aware of their status

  • % aware of their positive HIV status taking ART

  • % on ART with a viral load < 1000 copies/ml

Other outcomes

  • Prevalence of health risk factors and behaviours 

  • Cost-effectiveness

  • Process evaluation measures 

Primary outcome

  • % of youth with HIV with a viral load < 1000 copies/ml

Study Design
CHIEDZA Services

As of June 2022, the trial has ended. Enquiries can be made to gain information about the trial.


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